Clarke’s first law comes to mind:
"When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.“
So, eventually, it will be done. It may take may more decades or a few centuries. Several colonisations have needed more than one or two attempts. But in the end, they succeeded with better technology. So Mars and other currently deadly places will be colonised. Probably with technology indistinguishable from magic. dataare.cool/@anandamide/11311…