"We knew from genome analysis that there was something weird about the platypus's metabolic control system because they basically lack a functional stomach."
yet another bizarre thing about the platypus to add to the list
it makes sense I mean even monkeys wanna eat rotten fruit to get drunk off the minor alcohol content. Humanity has a rich history of consuming venom from various animals like frogs in order to get high. If it turns out, there’s a medical benefit then hey, bonus! I mean, we are a species where if you google “can I get high off smoking [thing]” there are lots of results.
@smiddi "But to get to a drug is a very long journey. We still have to learn a lot more about how this platypus hormone actually works." So. That very long journey was turned out to be just a bit under 8 years. Not bad.
@nblr @smiddi It was less than 8 years; Ozempic was licensed in the USA in 2017, not 2016 (it was in development earlier; liraglutide, a relative, was approved for human use in the EU in 2009, so the BBC were VERY late to the party).
That's really very cool. There is no antidote to the extreme pain caused by platypus venom. (I am not assuming you don't know, I just like telling people. )
I was reading this stuff too. It seems like the key difference with the monotreme version is it lasts longer in the gut. The articles don't say so but that sounds like it could point to an oral version. Did that happen in the intervening nine years, or is it still injection only?
I've been on oral semaglutide for three years at this point. (The quantity required to ensure an effective dose survives passage through the gut is about 500-1000 times more than the injectable version.)
#OtD 3 Feb 1909 Simone Weil, French philosopher, mystic, and activist, was born. She fought against the fascists in the Spanish civil war and again in the French resistance. She died in the UK in 1943, after refusing to eat more than French rations stories.workingclasshistory.co…
Achja ihr Sofortprogramm wurde einstimmig beschlossen, man hat natürlich nie mit der AfD zusammengearbeitet und wir Faulenzer sollen mehr arbeiten. Achja und man ist ja Christlich, Weil man will ja Kreuze und Religionsunterricht.
Well, I guess plenty of Latinos voted for Trump because they assumed a the-boat-is-full mentality. And when the boat is full all kinds of things can happen.
Wenn ich so drüber nachdenke, hätte ich lieber einen Inhaber (Robert Pattinson), der sich im Kleinkrieg befindet mit der Inhaberin des Eisenwarenladens gegenüber (Kristen Stewart).
NYU Law professor Noah Rosenblum posted on Bluesky yesterday that “[t]here has never been a larger gap in my (admittedly quite short) professional life between how lay folks and law profs are talking about what is happening in government right now. So much of what Trump is doing is just blatantly illegal — often in several ways at once.”
It seems obvious that Trump and Musk are running the basic play we’ve seen before from Musk and other Silicon Valley billionaires–move fast, break things (with “things” very much including the law), and then dare folks to try and do something about it.
The Democrats "gotcha! lol" approach to politics is negligent. There's no mystery here about what to do nor what needs to be done--they're simply not doing it. They prefer tweeting and fundraising to doing their jobs, it seems. The entire party needs to be fired.
By Samuel Bagenstos NYU Law professor Noah Rosenblum posted on Bluesky yesterday that “[t]here has never been a larger gap in my (admittedly quite short)...
A year ago, we decided to shutter UbuWeb. Not really shutter it, per se, but instead to consider it complete. After nearly 30 years, it felt right. But now, with the political changes in America and elsewhere around the world, we have decided to restart our archiving and regrow Ubu. In a moment when our collective memory is being systematically eradicated, archiving reemerges as a strong form of resistance, a way of preserving crucial, subversive, and marginalized forms of expression. We encourage you to do the same. All rivers lead to the same ocean: find your form of resistance, no matter how small, and go hard. It's now or never. Together we can prevent the annihilation of the memory of the world.
Auf YouTube findest du die angesagtesten Videos und Tracks. Außerdem kannst du eigene Inhalte hochladen und mit Freunden oder gleich der ganzen Welt teilen.
How Trump is targeting wind and solar energy – and delighting big oil | Donald Trump | The Guardian (Me: Burning down the house for today’s profit is GOP/Trump mantra!)
How Trump is targeting wind and solar energy – and delighting big oil | Donald Trump | The Guardian (Me: Burning down the house for today’s profit is GOP/Trump mantra!)
Source: How Trump is targeting wind and solar energy – and delighting big oil | Donald Trump | The Guardian
How Trump is targeting wind and solar energy – and delighting big oil | Donald Trump | The Guardian (Me: Burning down the house for today’s profit is GOP/Trump mantra!)
Wenn wir mit Grönland sprechen wegen einer Mitgliedschaft in der EU (nicht mehr nur assoziiert gem. Art. 198 AEUV), dann hätte die EU eine Grenze mit Kanada.
Kanada könnte - zumindest technisch & politisch/kulturell gesehen - Mitglied der Europäischen Union werden, weil es grenzt ja an Dänemark.
The exponential rise in microplastic pollution over the past 50 years may be reflected in increasing contamination in human brains, according to a new study.
Wirklich neu sind die zehn Punkte für mehr Sicherheit nicht. Doch die Grünen wollen im Wahlkampf noch einmal Unterschiede zur Union aufzeigen - ohne Schwarz-Grün auszuschließen.
Shopify has been supporting Nazis (by not banning them from their platform) for a long time and Shopify's management is heavily right-leaning. But it's not just that. The RubyOnRails leader ist also a Trump fan. The Ruby ecosystem seems to be a bad place. indieweb.social/@jgarber/11393…
Shopify’s a Nazi bar and their outsized influence in the Ruby community remains problematic for the health of the language. mstdn.ca/@jace/113935853978233…
Shopify’s a Nazi bar and their outsized influence in the Ruby community remains problematic for the health of the language. mstdn.ca/@jace/113935853978233…
Tobi Lutke, CEO of Shopify, Canada's second-largest company, is defending Trump’s tariff demands, and is blaming the Canadian Govt for not stopping trade war.
Absolutely disrespectfully, Tobi Lutke is a bootlicking traitorous dipshit. I think we need to start cancelling our Shopify accounts. We have our own tech bro wannabe oligarchy in Canada and they need to be shut down before they grow like the ones down south.
If there are better Canadian alternatives to Shopify, please share below.
Another mouse!!!!!! I hear this one’s about two inches long. Much bigger than the other one. Bun dad opened the pantry and it was on one of the shelves. They called the property but the property already plugged the holes so they’re not sure what can be done. I am in my room for now. Out of the way.
please don’t use glue traps, they’re cruel. If you want to use traps, then use the kind that is a little wire cage that closes when the mouse touches the bait inside, trapping them without killing or injuring them, so that they can be released outside/further away where they won’t bother people.
@enby_of_the_apocalypse @ChrisHolladay the apartment closed off the areas they thought mice were able to crawl through except behind the fridge- which is exactly where it ran to this morning and just now. They didn’t pull the fridge out last time (too much work) but they’ll have to this time
But you cannot fight the weapon of the future with the weapons of the last war. Therefore, only anti-social forces are effective against social forces.
Der Staatsstreich kommt per Kontoauszug - Elon Musk hat jetzt Zugriff auf alle Zahlungen, die das Finanzministerium auslöst - und damit auch direkte Einblicke in die Geschäfte seiner Konkurrenzunternehmen mit Regierungsverträgen. Na Prost.
US-Präsident Trump will Finanzhilfen für Südafrika auf Eis legen
US-Präsident Trump nimmt Südafrika ins Visier: Die dortige Regierung konfisziere Landbesitz und behandele "bestimmte Klassen" schlecht. Deshalb würden alle Finanzhilfen auf Eis gelegt. Die Regierung in Pretoria widerspricht. Von S. Ueberbach.
ich find's Klasse! Er macht einen auf Diktator und ich kenn Leute die finden ihn für seine Sachen super. Aussage: er macht zumindestens das was er gesagt hat!
You get, what you want!!
Außerdem, ist es bei dem Chinesen auch so,.das Sie sagen, wer bei uns verkaufen will, muss auch bei uns im Land etwas aufbauen.
Da bis jetzt alles billig war, hat sich DA keiner so gross aufgeregt!!
Nach 16 Jahren mit Mutti, wäre Merz nun gerne die Vaterfigur der konservativen Wähler-Familie. Und weil er eine Zeit lang weg war, hat ihn die Familie sicherheitshalber gefragt, ob er eine Affäre hatte. Also neben der Familie. Niemals hat der Vati gesagt und verlegen was von Treue und Brandmauer gemurmelt. Und nun plant der Vati gerade an der Feier anlässlich seiner Beförderung, und auf dem Sitzplan im Adenauer-Saal sitzt die Familie zu seiner linken und eine unbekannte Alice zu seiner rechten.
Wenn sich Katzen anschmiegen, empfinden das viele Menschen als beruhigend. Aber gilt das auch, wenn die Katze ein Roboter ist? Ja, sagen Forschende, aber nur unter einer Bedingung.
Mit den Spiegeln in Bekleidungsgeschäft-Umkleidekabinen habe ich eigentlich selten Beef; vielmehr verstört mich immer wieder, dass die fürs Anprobieren abgelegte Tageskleidung hier immer schlagartig gammlig und abgetragen aussieht. Inklusive Schuhe.
It's not "America first." It's not about jobs or how "unfairly" other nations have treated us. It's for goddamn sure not about opioids and the border
No. It's THIS, right here. When Trump said "Make America Great Again" what he meant was back when rich people owned everything (including other people) and had all the money and didn't have to pay taxes because poor Americans funded the government by paying tariffs on imported goods
Dieser unglaubliche Sturm der Lügen der CDU: mit der AfD stimmen und es „gesellschaftliche Mitte“ nennen. Mit der AfD stimmen und dann überall behaupten: das war keine Zusammenarbeit. Quo vadis, CDU? Leider ahnen wir es.
Die Bilder gingen um die Welt: Der Chef von Spaniens Fußballverband küsste die Spielerin Jennifer Hermoso bei der WM-Siegesfeier 2023 auf den Mund. Nun hat der Prozess begonnen.
Oh thank you! Although I subscribe to your emailed newsletter, Phil, I didn’t pick up on this. Also I’m a new subscriber to all-access Scientific American because I know science communication may be limited. So I do hope my #Photography friends in particular here in Fediverse see and read your article!
I heard Trey Ratliff recounting his efforts compiling 50 photos for a wall size cityscape he took in Dubai that was paid for by an ultra rich businessman. He said 10 computers were linked and it still took 10 hours to create the mega resolution file needed to print the wall mural of his work. At that time, it was mind-boggling to me, about 8 years ago.
And yet another #astrophotography from last years galaxy season. (Slowly filling my pixelfed 😉)
This one is M81 and M82, Bodes and the cigar galaxy. If the weather allows for it this is another possible candidate to reshoot for this years galaxy season.
Global stock markets take a tumble, Thanks to Trump and his tariff rumble. Investors are wary, Economies are scary, As they weather the market's wild grumble.
Brian Tatosky
Als Antwort auf Charlie Stross • • •Just the sort of thing that a nitwit politician would wave in front of the press as a waste of taxpayer money.
Instead look what science might lead us to. Amazing
Peter Cohen
Als Antwort auf Charlie Stross • • •Brian Fenton
Als Antwort auf Charlie Stross • • •"We knew from genome analysis that there was something weird about the platypus's metabolic control system because they basically lack a functional stomach."
yet another bizarre thing about the platypus to add to the list
Infoseepage
Als Antwort auf Charlie Stross • • •kurtseifried (he/him)
Als Antwort auf Charlie Stross • • •Matilda T. Zombie Queen
Als Antwort auf Charlie Stross • • •Mick 🇨🇦
Als Antwort auf Charlie Stross • • •Tom
Als Antwort auf Charlie Stross • • •smiddi
Als Antwort auf Charlie Stross • • •Charlie Stross
Als Antwort auf smiddi • • •~n
Als Antwort auf Charlie Stross • • •"But to get to a drug is a very long journey. We still have to learn a lot more about how this platypus hormone actually works."
So. That very long journey was turned out to be just a bit under 8 years. Not bad.
Charlie Stross
Als Antwort auf ~n • • •~n
Als Antwort auf Charlie Stross • • •Democracy Dies in Dumbass
Als Antwort auf Charlie Stross • • •GinevraCat
Als Antwort auf Charlie Stross • • •Jef Poskanzer
Als Antwort auf Charlie Stross • • •I was reading this stuff too. It seems like the key difference with the monotreme version is it lasts longer in the gut. The articles don't say so but that sounds like it could point to an oral version. Did that happen in the intervening nine years, or is it still injection only?
But in any case, I ❤️
Charlie Stross
Als Antwort auf Jef Poskanzer • • •